The search for longevity and renewed quality of life is as old as mankind. Bio-identical hormones have been in use for thousands of years. The first written records of their use goes back to ancient China where aging female nobility routinely ingested dried young women's crystallized urine to counteract the symptoms associated with menopause and promote longer, more productive, and vigorous lives. The reason for this type of therapy was that young women's urine contained metabolic waste products of estrogen, progesterone, and testosterone. Throughout history, you can find references to the use of young women's urine to help older women with problems of aging. Ancient Greek and Roman physicians used plant and animal products to attempt to slow or turn back the clock. Aristotle referred to the age at menopause being 40 years. Juan Ponce de Leon, born in 1474, sailed to the New World in search of the fountain of youth.